ACC Long : instructions for use , the price of 600 mg , real counterparts of effervescent tablets ACC Long

Category Medications | September 18, 2016 23:01

Contents:

  • ACC Long tablets effervescent 600mg instructions for use
    • release form and composition
    • Pharmacological action
    • Indications
    • Contraindications
    • Dosage and Administration
    • Side effects
    • Cautions
    • Analogs
    • terms and conditions of storage
    • ACC Long 600mg price

ACC Long - drug group mucolytics in the treatment of diseases of the respiratory tract, accompanied by difficulty in sputum.Patients with chronic bronchitis and cystic fibrosis drug is recommended for prophylaxis to reduce the frequency and severity of the acute stage.

release form and composition

ACC Long comes in the form of water-soluble tablets, 6, 10 and 20 tablets in a tube.The tube is placed in a cardboard box with instruction.

main active ingredient - acetylcysteine.In 1 tablet contains 600 mg of acetylcysteine.

Auxiliary components: carbonate and sodium carbonate, ascorbic acid, lactose, sodium citrate dihydrate, mannitol, sodium saccharin dihydrate, citric acid, sodium cyclamate, flavoring blackberry.

tablets are white, with a flat surface and the dividing line.Upon dissolution of the tablet in 100 ml of water clear colorless solution is formed with blackberry flavor.

Pharmacological action

Pharmacodynamics. Acetylcysteine ​​- a derivative of the amino acid cysteine.Mucolytic action of acetylcysteine ​​is due to its chemical structure: to the compound molecule is present a free sulfhydryl group that breaks the disulfide bonds of acid mucopolysaccharides sputum.As a result of bronchial mucus becomes less viscous, which facilitates its evacuation from the lumen of the bronchi and expectoration.Acetylcysteine ​​acts on a mucous sputum or purulent character.

Sulfigdrilnye acetylcysteine ​​group of molecules capable of binding chemical radicals, thus neutralizing their negative effects on the body and providing antioxidant effect.In addition, acetylcysteine ​​enhances the glutathione synthesis - a main body of protective factors, has toxic effect.While diseases of the respiratory tract occurs oxidative stress and general intoxication of the organism.Providing anti-oxidant and anti-toxic effect, acetylcysteine ​​inhibits the transition to chronic diseases and accelerates the recovery of the patient.

pharmacokinetics. drug is rapidly absorbed, broken down in the liver to the pharmacologically active metabolite of cysteine ​​and inactive connections - diatsetiltsisteina, cystine, and later - mixed disulfides.Bioavailability is about 10%.After 1-3 hours after application of the active substance concentration in plasma reaches a maximum.With blood proteins binds 50% acetylcysteine.After digestion and the provision of therapeutic action of acetylcysteine ​​inactive metabolites excreted by the kidneys.The half-life of about 60 minutes.In functional disorders of the liver this time increased to 8 hours.

Indications

ACC Long appointed in diseases of the respiratory system characterized by the presence of viscous sputum.It:

  • laryngotracheitis;
  • acute and chronic bronchitis;
  • obstructive bronchitis;
  • bronchiolitis;
  • bronchiectasis;
  • asthma;
  • pneumonia;
  • cystic fibrosis;
  • acute and chronic forms of sinusitis;
  • otitis media.

Contraindications Contraindications to the use of the drug are:

  • idiosyncrasy acetylcysteine ​​or auxiliary components of the drug;
  • age of 14 years;
  • pregnancy and during breastfeeding.

Regarding the appointment of the drug to pregnant and lactating women, sufficient clinical data available.Therefore, the use of ACC Long preparation is possible only in situations where the intended benefits to the mother outweighs the potential risk to the fetus.

Dosage and Administration

standard recommended dosage ACC Long is 600 mg acetylcysteine ​​(1 tablet) per day.The effervescent tablet is dissolved in a beaker of boiling, cooled to room temperature, water.Taken after meals.The prepared solution should drink immediately after the dissolution of the tablet.In exceptional cases, you can leave the facility prepared for no longer than 2 hours.

dissolving tablets should be glass (not metal) bowl, avoid contact with the tires quickly and oxidizing agents.Upon contact with the rubber and metal sulphides are formed with a characteristic odor.

course of drug treatment for mild colds, accompanied by cough, is 5-7 days.When prolonged inflammatory processes, as well as in the treatment of chronic bronchitis course duration of therapy is determined by your doctor.

Side effects

The drug is usually well tolerated.Rarely can occur:

  • headache;
  • stomatitis (inflammation of the oral mucosa);
  • tinnitus.

rarely possible:

  • dyspepsia - nausea and vomiting, diarrhea, heartburn;
  • lowering blood pressure;
  • tachycardia (rapid heart rate);
  • allergic reactions - itching and rash, urticaria, bronchospasm (bronchial hyperresponsiveness in patients with patients);
  • bleeding (as a hypersensitivity reaction to acetylcysteine).

If overdose is marked indigestion manifested by nausea and vomiting, diarrhea, heartburn and pain in the stomach.If you have side effects or signs of overdose should stop taking the drug and consult a doctor immediately.To date, life-threatening, serious side effects from the drug were observed.

Cautions

wary drug is indicated for:

  • exacerbation of gastric and / or duodenal ulcer;
  • states, accompanied by expectoration of blood;
  • pulmonary hemorrhage;
  • varicose veins of the esophagus;
  • bronchial asthma;
  • diseases of the adrenal glands;
  • renal and hepatic failure (to prevent the accumulation of nitrogen-containing compounds in the body).

the appointment and use of the drug is important to consider ACC Long:

  • drinking plenty of fluids during treatment enhances the mucolytic effect of acetylcysteine;
  • information for patients with diabetes: 1 tablet ACC Long matches XE 0.01 (bread units);
  • tablets ACC Long contain sodium compounds, which should take into account patients staying on a salt-free diet;
  • acetylcysteine ​​effect on the histamine metabolism, so you should not take the pills for a long time in patients with histamine intolerance - this may cause hypersensitivity symptoms (itching, rhinitis, headache);
  • the appointment ACC Long patients with obstructive bronchitis and bronchial asthma requires strict systematic control of bronchial obstruction;
  • tablets contain lactose ACC Long, therefore are not assigned to patients with rare hereditary form of galactose intolerance, lactase deficiency or glucose-galactose syndrome malabsorption;
  • smoking concurrent use acetylcysteine ​​and antitussives, since inhibition of the cough reflex induced antitussive drugs can lead to stagnation of mucus and the development of secondary infection until pneumonia;
  • acetylcysteine ​​in combination with nitroglycerin vasodilator action last intensifies;
  • acetylcysteine ​​is incompatible with antibiotics - tetracycline, erythromycin, amphotericin B, penicillins and cephalosporins (while the application of reduced bioavailability of antibiotics, so the need for a comprehensive treatment antibiotics are taken not earlier than 2 hours after administration of acetylcysteine).

Analogs

similar drugs (acetylcysteine ​​with a part of) are: Acetylcysteine ​​Hemofarm Acetylcysteine ​​Herds, Mukobene, Mukoneks, Fluimucil, Tussikom, Ekzomyuk, Mukosolvin, Mukomist, N-AC-Ratiopharm.

Terms and conditions of storage

drug is stored at a temperature no higher than 30 ° C, protected from sunlight.After each tube taking the drug should be tightly closed.Keep tablets out of the reach of children.

shelf life of the drug ACC Long - 3 years.After the end of the period indicated on the packaging, the drug can not be used.

ACC Long 600mg price

ACC Long effervescent tablets 600 mg, 10 pcs.- From 257 rubles.