ACC Long - drug group mucolytics in the treatment of diseases of the respiratory tract, accompanied by difficulty in sputum.Patients with chronic bronchitis and cystic fibrosis drug is recommended for prophylaxis to reduce the frequency and severity of the acute stage.
ACC Long comes in the form of water-soluble tablets, 6, 10 and 20 tablets in a tube.The tube is placed in a cardboard box with instruction.
main active ingredient - acetylcysteine.In 1 tablet contains 600 mg of acetylcysteine.
Auxiliary components: carbonate and sodium carbonate, ascorbic acid, lactose, sodium citrate dihydrate, mannitol, sodium saccharin dihydrate, citric acid, sodium cyclamate, flavoring blackberry.
tablets are white, with a flat surface and the dividing line.Upon dissolution of the tablet in 100 ml of water clear colorless solution is formed with blackberry flavor.
Pharmacodynamics. Acetylcysteine - a derivative of the amino acid cysteine.Mucolytic action of acetylcysteine is due to its chemical structure: to the compound molecule is present a free sulfhydryl group that breaks the disulfide bonds of acid mucopolysaccharides sputum.As a result of bronchial mucus becomes less viscous, which facilitates its evacuation from the lumen of the bronchi and expectoration.Acetylcysteine acts on a mucous sputum or purulent character.
Sulfigdrilnye acetylcysteine group of molecules capable of binding chemical radicals, thus neutralizing their negative effects on the body and providing antioxidant effect.In addition, acetylcysteine enhances the glutathione synthesis - a main body of protective factors, has toxic effect.While diseases of the respiratory tract occurs oxidative stress and general intoxication of the organism.Providing anti-oxidant and anti-toxic effect, acetylcysteine inhibits the transition to chronic diseases and accelerates the recovery of the patient.
pharmacokinetics. drug is rapidly absorbed, broken down in the liver to the pharmacologically active metabolite of cysteine and inactive connections - diatsetiltsisteina, cystine, and later - mixed disulfides.Bioavailability is about 10%.After 1-3 hours after application of the active substance concentration in plasma reaches a maximum.With blood proteins binds 50% acetylcysteine.After digestion and the provision of therapeutic action of acetylcysteine inactive metabolites excreted by the kidneys.The half-life of about 60 minutes.In functional disorders of the liver this time increased to 8 hours.
ACC Long appointed in diseases of the respiratory system characterized by the presence of viscous sputum.It:
Contraindications Contraindications to the use of the drug are:
Regarding the appointment of the drug to pregnant and lactating women, sufficient clinical data available.Therefore, the use of ACC Long preparation is possible only in situations where the intended benefits to the mother outweighs the potential risk to the fetus.
standard recommended dosage ACC Long is 600 mg acetylcysteine (1 tablet) per day.The effervescent tablet is dissolved in a beaker of boiling, cooled to room temperature, water.Taken after meals.The prepared solution should drink immediately after the dissolution of the tablet.In exceptional cases, you can leave the facility prepared for no longer than 2 hours.
dissolving tablets should be glass (not metal) bowl, avoid contact with the tires quickly and oxidizing agents.Upon contact with the rubber and metal sulphides are formed with a characteristic odor.
course of drug treatment for mild colds, accompanied by cough, is 5-7 days.When prolonged inflammatory processes, as well as in the treatment of chronic bronchitis course duration of therapy is determined by your doctor.
The drug is usually well tolerated.Rarely can occur:
If overdose is marked indigestion manifested by nausea and vomiting, diarrhea, heartburn and pain in the stomach.If you have side effects or signs of overdose should stop taking the drug and consult a doctor immediately.To date, life-threatening, serious side effects from the drug were observed.
wary drug is indicated for:
the appointment and use of the drug is important to consider ACC Long:
similar drugs (acetylcysteine with a part of) are: Acetylcysteine Hemofarm Acetylcysteine Herds, Mukobene, Mukoneks, Fluimucil, Tussikom, Ekzomyuk, Mukosolvin, Mukomist, N-AC-Ratiopharm.
drug is stored at a temperature no higher than 30 ° C, protected from sunlight.After each tube taking the drug should be tightly closed.Keep tablets out of the reach of children.
shelf life of the drug ACC Long - 3 years.After the end of the period indicated on the packaging, the drug can not be used.
ACC Long effervescent tablets 600 mg, 10 pcs.- From 257 rubles.