Acyclovir ophthalmic ointment : instructions for use , price, reviews, analogues acyclovir ophthalmic ointment

Category Medications | September 18, 2016 23:00

Contents:

  • acyclovir ophthalmic ointment instructions for use
    • Product form and composition
    • Pharmacological action
    • Indications
    • Contraindications
    • Dosage
    • Side effects
    • Cautions
    • Overdose
    • Analogs
    • terms and conditions of storage
    • Eye ointment Acyclovir price

Eye ointment Acyclovir belongs to the pharmacological group of drugs - antivirals.It is used in ophthalmology for the treatment of herpes viral infections that affect the eyes.Antiviral activity has the active ingredient of the drug - micronized acyclovir.

release form and composition

Eye ointment Acyclovir is a dosage form for use in ophthalmology.It is available in tubes, which contain 5 g of ointment.The carton pack ophthalmic ointment acyclovir contains one tube of ointment and instructions for use.The active ingredient is micronized drug acyclovir.Its concentration in a 1 ml volume of ointment is 30 mg.In addition to the main active ingredient ointment contains an auxiliary component of white petrolatum.The concent

ration of the active compound acyclovir ophthalmic ointment is sufficient to provide an antiviral action.

Pharmacological action

The active drug substance is an anti-viral agent.It relates to a synthetic nucleoside analogue of thymidine.Penetrating into the infected cell, acyclovir under the action of the viral thymidine kinase enzyme is converted to its active form - acyclovir triphosphate.It is embedded in the DNA (deoxyribonucleic acid, the genetic material is, contains information in the form of a specific sequence of nucleosides) of the virus and prevents further reading (transcription) information therefrom.It blocks further replication (reproduction) of the virus.Since normal cells have enzyme thymidine kinase, acyclovir has no adverse effect on them.Acyclovir ophthalmic ointment is effective mainly against herpes viruses - herpes simplex virus type 1 and 2 (Herpes simplex 1 and 2), herpes zoster virus (Varicella zoster).The drug blocks the less multiplication of cytomegalovirus (CMV), Epstein-Barr virus.

After applying the eye ointment, the active ingredient rapidly and almost completely adsorbed by the cells of the stratum corneum eye and periocular (parabulbarno) fiber.It penetrates well into the eyeball, accumulates in the vitreous body of the eye and in the aqueous humor.Small amounts of acyclovir absorbed into the systemic circulation, cross the placenta into the body of the growing fetus during pregnancy and in breast milk during lactation.

Indications

Application acyclovir ophthalmic ointment is indicated for the treatment of keratitis (inflammation of the cornea process) caused by susceptible to the active ingredient of the drug virus - the herpes virus, herpes zoster, cytomegalovirus and Epstein-Barr virus.

Contraindications

main contraindication to the use of acyclovir ophthalmic ointment is the idiosyncrasy of the active ingredient of the drug or its auxiliary components.During pregnancy and breast-feeding, the ointment can be used only if the benefits to the mother's body is much greater than the potential risk to the growing fetus or child.

Dosage

Eye ointment Acyclovir is applied in the form of installation in the lower conjunctival sac of a small strip with a length of about 10 mm.This installation run 5 times a day at intervals of not less than 4 hours.The duration of treatment of eye ointment Acyclovir is the whole period of corneal disease and another 3 days after the improvement of the condition and reduce the severity of the manifestations of the pathological process.

Side effects

Application acyclovir ophthalmic ointment in a small number of cases can lead to the development of these side effects:

  • Burning sensation after laying the ointment into the lower conjunctival sac - the intensity of burning depends on the severity of individual intolerance to the drug.
  • Development superficial keratopathy - degenerative-dystrophic process in the cells of the surface layer of the cornea.
  • Conjunctivitis - reactive inflammation of the conjunctiva eyes.
  • development of allergic reactions in case of hypersensitivity (hypersensitization) to the drug, when the suction system in the bloodstream - may develop a rash on the skin, it itching, hives (rash with characteristic small swelling of the skin, which resembles a sting).Very rarely it may develop severe allergic reactions such as anaphylactic shock (the development of multiple organ failure on a background of the progressive reduction of systemic blood pressure).

In the case of any side effect, you must stop using the product and consult a physician.

Cautions

Before the start of the drug is necessary to carefully study the instructions for its use.It is necessary to pay attention to some of the features in the use of eye ointment Acyclovir:

  • The first application of the ointment may cause light burning in the conjunctiva, which in most cases resolve spontaneously.
  • During the course of treatment of eye ointment Acyclovir wearing contact lenses is not recommended.
  • Effect on the speed of psychomotor reactions and concentration lacking.

drug in pharmacies without prescription.If you have questions or doubts in respect of its application, it is necessary to consult a doctor.

Overdose

cases significantly exceeding the dose and the corresponding reaction of the organism is not known.Perhaps the development of adverse ophthalmic acyclovir ointment.

Analogs

ophthalmic ointment, which also contains acyclovir as the main active ingredient is - Zovirax.

Terms and conditions of storage

shelf life of the drug is 5 years, in case it has not been applied.After printing, eye ointment can be stored for 30 days.Keep necessary in the dark, place inaccessible to children at temperature not above + 25 ° C

Eye ointment Acyclovir price

Acyclovir Ointment eye 3%;aluminum tube 5 g - 64 rubles.